Title : Busulfan conditioning enhances engraftment of hematopoietic donor-derived cells in the brain compared with irradiation.

Pub. Date : 2013 Apr

PMID : 23423338






1 Functional Relationships(s)
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1 MCP-1, a key regulator of monocyte transmigration, showed long-term elevation in busulfan-conditioned brain, whereas irradiated brains showed long-term elevation of the proinflammatory chemokine interleukin 1alpha (IL-1alpha), with increased in situ proliferation of resident microglia, and significant increases in the relative number of amoeboid activated microglia in the brain. Busulfan C-C motif chemokine ligand 2 Homo sapiens