Title : Resveratrol abrogates alcohol-induced cognitive deficits by attenuating oxidative-nitrosative stress and inflammatory cascade in the adult rat brain.

Pub. Date : 2013 May

PMID : 23422878






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1 Correlatively, the results of the present study revealed that treatment with resveratrol significantly prevented cognitive deficits induced by chronic ethanol exposure not only by modulating oxido-nitrosative stress but also by attenuating the enhanced levels of pro-inflammatory cytokines (TNF-alpha and IL-1beta), NF-kbeta and caspase-3 in different brain regions of ethanol treated rats. Resveratrol interleukin 1 beta Rattus norvegicus