Title : Evaluation of histone 3 lysine 27 trimethylation (H3K27me3) and enhancer of Zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas.

Pub. Date : 2013 Sep

PMID : 23414300






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 H3F3A mutations are seen in ~30% of pediatric glioblastoma (GBMs) and involve either the lysine residue at position 27 (K27M) or glycine at position 34 (G34R/V). Glycine H3.3 histone A Homo sapiens