Title : Brain nitric oxide synthases in the interleukin-1β-induced activation of hypothalamic-pituitary-adrenal axis.

Pub. Date : 2012

PMID : 23406756






2 Functional Relationships(s)
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1 RESULTS: IL-1beta significantly increased plasma ACTH, corticosterone and IL-1beta levels during 2 h after ip administration. Corticosterone interleukin 1 beta Rattus norvegicus
2 IL-1 receptor antagonist was able to abolish the stimulatory effect of IL-1beta on plasma ACTH and corticosterone levels and significantly, but not totally, reduced plasma IL-1beta level. Corticosterone interleukin 1 beta Rattus norvegicus