Title : Function of the hypothalamo-neurohypophysial system in rats with myocardial infarction is modified by melatonin.

Pub. Date : 2012

PMID : 23406755






4 Functional Relationships(s)
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1 The present study was undertaken to evaluate the possible regulatory role of melatonin in the vasopressin and oxytocin release in rats with myocardial infarction. Melatonin arginine vasopressin Rattus norvegicus
2 In pinealectomized rats substituted with melatonin, pineal indole amine was seen to inhibit oxytocin release and stimulate vasopressin secretion. Melatonin arginine vasopressin Rattus norvegicus
3 CONCLUSIONS: (i) CAL-induced myocardial infarction is the reason for increased hypothalamo-neurohypophysial system activity in rats; melatonin plays the role of inhibitory neuromodulator of vasopressin and oxytocin release in this state. Melatonin arginine vasopressin Rattus norvegicus
4 (iii) Melatonin stimulates vasopressin (but decreases oxytocin) release in pinealectomized rats with myocardial infarction. Melatonin arginine vasopressin Rattus norvegicus