Pub. Date : 2013 Apr
PMID : 23406438
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This FKBP5 polymorphism by disease status interaction was paralleled by the extent of plasma cortisol and ACTH suppression following dexamethasone administration, with a reduced suppression only observed in depressed patients carrying the T allele. | Dexamethasone | proopiomelanocortin | Homo sapiens |
| 2 | Only depressed patients carrying the FKBP5 rs1360780 risk allele showed significant GR resistance compared with healthy controls, as measured by dexamethasone-induced FKBP5 mRNA induction in peripheral blood cells and suppression of plasma cortisol and ACTH concentrations. | Dexamethasone | proopiomelanocortin | Homo sapiens |