Title : GRL-0519, a novel oxatricyclic ligand-containing nonpeptidic HIV-1 protease inhibitor (PI), potently suppresses replication of a wide spectrum of multi-PI-resistant HIV-1 variants in vitro.

Pub. Date : 2013 May

PMID : 23403426






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 GRL-0519 blocked the infectivity and replication of HIV-1NL4-3 variants selected by up to a 5 muM concentration of ritonavir, lopinavir, or atazanavir (EC50, 0.0028 to 0.0033 muM). Lopinavir nuclear receptor subfamily 3 group C member 1 Homo sapiens