Title : Differential modulation of EAE by α9*- and β2*-nicotinic acetylcholine receptors.

Pub. Date : 2013 Mar

PMID : 23399696






2 Functional Relationships(s)
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1 On the other hand, beta2 KO mice fail to recover from peak measures of disease severity regardless of nicotine treatment, despite retaining sensitivity to nicotine"s attenuation of disease severity. Nicotine hemoglobin, beta adult minor chain Mus musculus
2 Our data thus suggest that beta2*- and alpha9*-nAChRs, in addition to alpha7-nAChRs, have different roles in endogenous and nicotine-dependent modulation of immune functions and could be exploited as therapeutic targets to modulate inflammation and autoimmunity. Nicotine hemoglobin, beta adult minor chain Mus musculus