Pub. Date : 2013 Mar
PMID : 23385093
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A common modification of human long-lived proteins is spontaneous isomerisation of aspartate residues, and its biological importance can be inferred from the ubiquitous presence of protein isoaspartate methyl transferase (PIMT), that repairs this damage. | Aspartic Acid | protein-L-isoaspartate (D-aspartate) O-methyltransferase | Homo sapiens |
| 2 | A common modification of human long-lived proteins is spontaneous isomerisation of aspartate residues, and its biological importance can be inferred from the ubiquitous presence of protein isoaspartate methyl transferase (PIMT), that repairs this damage. | Aspartic Acid | protein-L-isoaspartate (D-aspartate) O-methyltransferase | Homo sapiens |
| 3 | If PIMT is present, L-isoAsp may be reverted to L-Asp, however there appears to be no prospect of reversing D-isoAsp formation in aged proteins. | Aspartic Acid | protein-L-isoaspartate (D-aspartate) O-methyltransferase | Homo sapiens |