Pub. Date : 2013 Apr
PMID : 23381945
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Wwox expression may predict benefit from adjuvant tamoxifen in randomized breast cancer patients. | Tamoxifen | WW domain containing oxidoreductase | Homo sapiens |
| 2 | Reduced or absent Wwox expression has recently been associated with tamoxifen resistance in breast cancer and has also been proposed as a candidate predictive marker for treatment. | Tamoxifen | WW domain containing oxidoreductase | Homo sapiens |
| 3 | We aimed to investigate the correlation of Wwox expression with the outcome of tamoxifen treatment by examining tissues from 912 randomized breast cancer patients. | Tamoxifen | WW domain containing oxidoreductase | Homo sapiens |
| 4 | Our results indicate that patients with high expression of Wwox may gain more benefit from treatment with tamoxifen. | Tamoxifen | WW domain containing oxidoreductase | Homo sapiens |