Title : Oral exposure to atrazine modulates hormone synthesis and the transcription of steroidogenic genes in male peripubertal mice.

Pub. Date : 2013 Apr 1

PMID : 23376530






2 Functional Relationships(s)
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1 We also found that the transcript levels of the steroidogenic enzyme genes p450scc, p450 17alpha1 and 17beta-HSD were significantly reduced in the testes of mice exposed to 100 and 200 mg/kg ATZ for 3weeks. Atrazine cytochrome P450, family 11, subfamily a, polypeptide 1 Mus musculus
2 Given the results of the present study and previous reports, it is possible that ATZ reduces the T concentration in peripubertal male mice by affecting the transcription of steroidogenic genes, such as p450scc, p450 17a1 and 17beta-HSD. Atrazine cytochrome P450, family 11, subfamily a, polypeptide 1 Mus musculus