Title : Regulation of progenitor cell proliferation and neuronal differentiation in enteric nervous system neurospheres.

Pub. Date : 2013

PMID : 23372773






1 Functional Relationships(s)
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1 Treatment of both mouse and human neurospheres with the gamma-secretase inhibitor N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester (DAPT) reduced expression of the transcription factors Hes1 and Hes5, demonstrating inhibition of Notch signaling. dapt hes family bHLH transcription factor 1 Homo sapiens