Title : Pituitary homeobox 2 (PITX2) protects renal cancer cell lines against doxorubicin toxicity by transcriptional activation of the multidrug transporter ABCB1.

Pub. Date : 2013 Aug 1

PMID : 23354914






1 Functional Relationships(s)
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1 Silencing of PITX2 by siRNA downregulates ABCB1 and induces a greater chemotherapeutic response to doxorubicin in A498 cells, as determined by MTT cell viability and clonogenic survival assays. monooxyethylene trimethylolpropane tristearate paired like homeodomain 2 Homo sapiens