Title : Salinomycin induces apoptosis and senescence in breast cancer: upregulation of p21, downregulation of survivin and histone H3 and H4 hyperacetylation.

Pub. Date : 2013 Apr

PMID : 23352703






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Salinomycin induces apoptosis and senescence in breast cancer: upregulation of p21, downregulation of survivin and histone H3 and H4 hyperacetylation. salinomycin H3 histone pseudogene 16 Homo sapiens
2 Interestingly, treatment with low concentrations of Salinomycin induced a transient G1 arrest at earlier time point and G2 arrest at later point and senescence associated with enlarged cellmorphology, upregulation of p21 protein, increase in histone H3 and H4 hyperacetylation and expression of SA-beta-Gal activity. salinomycin H3 histone pseudogene 16 Homo sapiens