Pub. Date : 2012 May 15
PMID : 23344002
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cholesterol-lowering Action of BNA-based Antisense Oligonucleotides Targeting PCSK9 in Atherogenic Diet-induced Hypercholesterolemic Mice. | Oligonucleotides | proprotein convertase subtilisin/kexin type 9 | Mus musculus |
| 2 | The cholesterol-lowering potential of anti-PCSK9 antisense oligonucleotides (AONs) modified with bridged nucleic acids (BNA-AONs) including 2",4"-BNA (also called as locked nucleic acid (LNA)) and 2",4"-BNA(NC) chemistries were demonstrated both in vitro and in vivo. | Oligonucleotides | proprotein convertase subtilisin/kexin type 9 | Mus musculus |