Pub. Date : 2013 Mar 21
PMID : 23340159
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We demonstrate that activation of porcine CAR by the human CAR (hCAR) ligand CITCO (6-(4-chlorophenyl)-imidazo[2,1-b]thiazole-5-carbaldehyde) leads to an up-regulation of both transporters, whereas the mouse-specific CAR ligand TCPOBOP (1,4-bis-[2-(3,5-dichloropyridyloxy)]benzene) had no effect on transporter expression. | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | nuclear receptor subfamily 1 group I member 3 | Homo sapiens |
2 | We demonstrate that activation of porcine CAR by the human CAR (hCAR) ligand CITCO (6-(4-chlorophenyl)-imidazo[2,1-b]thiazole-5-carbaldehyde) leads to an up-regulation of both transporters, whereas the mouse-specific CAR ligand TCPOBOP (1,4-bis-[2-(3,5-dichloropyridyloxy)]benzene) had no effect on transporter expression. | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | nuclear receptor subfamily 1 group I member 3 | Homo sapiens |
3 | We demonstrate that activation of porcine CAR by the human CAR (hCAR) ligand CITCO (6-(4-chlorophenyl)-imidazo[2,1-b]thiazole-5-carbaldehyde) leads to an up-regulation of both transporters, whereas the mouse-specific CAR ligand TCPOBOP (1,4-bis-[2-(3,5-dichloropyridyloxy)]benzene) had no effect on transporter expression. | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | nuclear receptor subfamily 1 group I member 3 | Homo sapiens |
4 | We demonstrate that activation of porcine CAR by the human CAR (hCAR) ligand CITCO (6-(4-chlorophenyl)-imidazo[2,1-b]thiazole-5-carbaldehyde) leads to an up-regulation of both transporters, whereas the mouse-specific CAR ligand TCPOBOP (1,4-bis-[2-(3,5-dichloropyridyloxy)]benzene) had no effect on transporter expression. | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | nuclear receptor subfamily 1 group I member 3 | Homo sapiens |
5 | We demonstrate that activation of porcine CAR by the human CAR (hCAR) ligand CITCO (6-(4-chlorophenyl)-imidazo[2,1-b]thiazole-5-carbaldehyde) leads to an up-regulation of both transporters, whereas the mouse-specific CAR ligand TCPOBOP (1,4-bis-[2-(3,5-dichloropyridyloxy)]benzene) had no effect on transporter expression. | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | nuclear receptor subfamily 1 group I member 3 | Homo sapiens |
6 | We demonstrate that activation of porcine CAR by the human CAR (hCAR) ligand CITCO (6-(4-chlorophenyl)-imidazo[2,1-b]thiazole-5-carbaldehyde) leads to an up-regulation of both transporters, whereas the mouse-specific CAR ligand TCPOBOP (1,4-bis-[2-(3,5-dichloropyridyloxy)]benzene) had no effect on transporter expression. | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | nuclear receptor subfamily 1 group I member 3 | Homo sapiens |