Title : Structure-activity relationship for FDA approved drugs as inhibitors of the human sodium taurocholate cotransporting polypeptide (NTCP).

Pub. Date : 2013 Mar 4

PMID : 23339484






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Screening studies identified 27 drugs as novel NTCP inhibitors, including irbesartan (Ki = 11.9 muM) and ezetimibe (Ki = 25.0 muM). Irbesartan solute carrier family 10 member 1 Homo sapiens