Pub. Date : 2013 Mar
PMID : 23337939
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Antiproliferative activity of daidzein and genistein may be related to ERalpha/c-erbB-2 expression in human breast cancer cells. | daidzein | estrogen receptor 1 | Homo sapiens |
| 2 | After treatment at various concentrations (1-200 microM for 72 h), the effect of daidzein and genistein on the proliferation of different cell types varied; these effects were found to be associated with ERalpha and c-erbB-2 expression. | daidzein | estrogen receptor 1 | Homo sapiens |
| 3 | Daidzein and genistein exhibited biphasic effects (stimulatory or inhibitory) on proliferation and ERalpha expression in MCF-7 cells. | daidzein | estrogen receptor 1 | Homo sapiens |
| 4 | In conclusion, the isoflavones daidzein and genistein showed anti-breast cancer activity, which was associated with expression of the ERalpha and c-erbB-2 receptors. | daidzein | estrogen receptor 1 | Homo sapiens |