Title : Concise synthesis of α-galactosyl ceramide from D-galactosyl iodide and D-lyxose.

Pub. Date : 2013 Mar 7

PMID : 23333444






1 Functional Relationships(s)
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1 The alpha-linked disaccharide obtained was subsequently transformed into alpha-galactosyl ceramide in four steps involving Z-selective Wittig olefination at C-1, stereo-inversion at C-4 using azide, one-pot reduction of azide and amidation, and global deprotection. Azides complement C4A (Rodgers blood group) Homo sapiens