Title : Nitroarachidonic acid prevents NADPH oxidase assembly and superoxide radical production in activated macrophages.

Pub. Date : 2013 May

PMID : 23318789






2 Functional Relationships(s)
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1 One of the immediate responses upon macrophage activation involves the production of superoxide radical (O2( -)) due to the NADPH-dependent univalent reduction of oxygen to O2( -) by the phagocytic NADPH oxidase isoform (NOX2), the activity of NOX2 being the main source of O2( -) in monocytes/macrophages. Superoxides cytochrome b-245, beta polypeptide Mus musculus
2 One of the immediate responses upon macrophage activation involves the production of superoxide radical (O2( -)) due to the NADPH-dependent univalent reduction of oxygen to O2( -) by the phagocytic NADPH oxidase isoform (NOX2), the activity of NOX2 being the main source of O2( -) in monocytes/macrophages. Superoxides cytochrome b-245, beta polypeptide Mus musculus