Pub. Date : 2013 Feb
PMID : 23303296
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Since SN-38 is metabolized to non-toxic SN-38-glucuronide by hepatic uridine diphosphate glucuronosyl transferase (UGT) 1A enzymes, UGT1A enzyme activities may influence adverse events of CPT-11. | Irinotecan | UDP glucuronosyltransferase family 1 member A complex locus | Homo sapiens |
2 | Since SN-38 is metabolized to non-toxic SN-38-glucuronide by hepatic uridine diphosphate glucuronosyl transferase (UGT) 1A enzymes, UGT1A enzyme activities may influence adverse events of CPT-11. | Irinotecan | UDP glucuronosyltransferase family 1 member A complex locus | Homo sapiens |
3 | Since SN-38 is metabolized to non-toxic SN-38-glucuronide by hepatic uridine diphosphate glucuronosyl transferase (UGT) 1A enzymes, UGT1A enzyme activities may influence adverse events of CPT-11. | Irinotecan | UDP glucuronosyltransferase family 1 member A complex locus | Homo sapiens |
4 | Since SN-38 is metabolized to non-toxic SN-38-glucuronide by hepatic uridine diphosphate glucuronosyl transferase (UGT) 1A enzymes, UGT1A enzyme activities may influence adverse events of CPT-11. | Irinotecan | UDP glucuronosyltransferase family 1 member A complex locus | Homo sapiens |
5 | Here, to identify the genetic factors that affect the adverse events of CPT-11, we determined the polymorphism in three UGT 1A isozyme genes in 45 inpatients with lung, colon, or stomach cancer. | Irinotecan | UDP glucuronosyltransferase family 1 member A complex locus | Homo sapiens |