Title : Prolonged survival and delayed progression of pancreatic intraepithelial neoplasia in LSL-KrasG12D/+;Pdx-1-Cre mice by vitamin E δ-tocotrienol.

Pub. Date : 2013 Apr

PMID : 23302291






1 Functional Relationships(s)
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1 delta-Tocotrienol treatment inhibited mutant Kras-driven pathways such as MEK/ERK, PI3K/AKT and NF-kB/p65, as well as Bcl-xL and induced p27. tocotrienol, delta thymoma viral proto-oncogene 1 Mus musculus