Title : Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.

Pub. Date : 2013 Jan 22

PMID : 23297231






1 Functional Relationships(s)
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1 Structural and complementary chemical analyses reveal an unexpected mechanism of inhibition involving covalent conjugation and CRM1-mediated hydrolysis of the natural products" lactone rings. Lactones exportin 1 Homo sapiens