Title : Transcription factors GATA-3 and RORĪ³t are important for determining the phenotype of allergic airway inflammation in a murine model of asthma.

Pub. Date : 2013 Feb 1

PMID : 23293351






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 GATA-3-overexpressing mice exhibited steroid-sensitive eosinophilic inflammation with goblet cell hyperplasia and mucus hyperproduction under Th2-biased conditions, and RORgammat-overexpressing mice developed steroid-insensitive neutrophilic inflammation under Th17-biased conditions. Steroids GATA binding protein 3 Mus musculus