Title : Regiospecificity and stereospecificity of human UDP-glucuronosyltransferases in the glucuronidation of estriol, 16-epiestriol, 17-epiestriol, and 13-epiestradiol.

Pub. Date : 2013 Mar

PMID : 23288867






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 UGT1A10 is highly active in the conjugation of the 3-OH in all these estriols, whereas UGT2B7 is the most active UGT toward one of the ring D hydroxyls, the 16-OH in estriol and 16-epiestriol, but the 17-OH in 17-epiestriol. 17-Epiestriol UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens