Title : Chimeric β-lactamases: global conservation of parental function and fast time-scale dynamics with increased slow motions.

Pub. Date : 2012

PMID : 23284969






1 Functional Relationships(s)
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1 In one such effort, chimeras of two class-A beta-lactamases - TEM-1 and PSE-4 - were created according to structure-guided protein recombination and selected for their capacity to promote bacterial proliferation in the presence of ampicillin (Voigt et al., Nat. Ampicillin CD248 molecule Homo sapiens