Title : The Smc5-Smc6 complex regulates recombination at centromeric regions and affects kinetochore protein sumoylation during normal growth.

Pub. Date : 2012

PMID : 23284708






2 Functional Relationships(s)
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1 A rad52 mutation that decreases centromeric, but not overall, levels of Rad52 foci in smc6 mutants suppresses the nocodazole sensitivity of these cells, suggesting that the Smc6-mediated regulation of recombination at centromeric regions impacts centromere-related functions. Nocodazole DNA repair protein SMC6 Saccharomyces cerevisiae S288C
2 A rad52 mutation that decreases centromeric, but not overall, levels of Rad52 foci in smc6 mutants suppresses the nocodazole sensitivity of these cells, suggesting that the Smc6-mediated regulation of recombination at centromeric regions impacts centromere-related functions. Nocodazole DNA repair protein SMC6 Saccharomyces cerevisiae S288C