Pub. Date : 2013 Jul
PMID : 23280610
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Deficiency of galectin-3, either hereditary or induced through application of chemical inhibitors, beta-lactose or TD139, supported survival and function of islet beta cells compromised by TNF-alpha + IFN-gamma + IL-1beta stimulus. | Lactose | lectin, galactose binding, soluble 3 | Mus musculus |
| 2 | Similarly, inhibition of galectin-3 by beta-lactose or TD139 reduced cytokine-triggered apoptosis of beta cells, leading to conclusion that endogenous galectin-3 propagates beta apoptosis in the presence of an inflammatory milieu. | Lactose | lectin, galactose binding, soluble 3 | Mus musculus |
| 3 | Similarly, inhibition of galectin-3 by beta-lactose or TD139 reduced cytokine-triggered apoptosis of beta cells, leading to conclusion that endogenous galectin-3 propagates beta apoptosis in the presence of an inflammatory milieu. | Lactose | lectin, galactose binding, soluble 3 | Mus musculus |