Title : Comparison of the effect of standard and novel immunosuppressive drugs on CMV-specific T-cell cytokine profiling.

Pub. Date : 2013 Feb 15

PMID : 23274966






2 Functional Relationships(s)
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1 For example, tacrolimus was more potent in inhibiting CMV-specific Th1 cytokines versus Th2, whereas MPA preferentially inhibited Th2 cytokines. Tacrolimus negative elongation factor complex member C/D Homo sapiens
2 In a comparison of the relative potency of each drug at different dosing ranges, tacrolimus had the strongest Th1 inhibitory effect (median inhibition of interferon-gamma at 97.5%; P=0.004-0.008) followed by sirolimus (median inhibition at 82.4%). Tacrolimus negative elongation factor complex member C/D Homo sapiens