Title : Icariin potentiates the antitumor activity of gemcitabine in gallbladder cancer by suppressing NF-κB.

Pub. Date : 2013 Feb

PMID : 23274410






1 Functional Relationships(s)
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1 In GBC-SD cells, icariin significantly inhibited both the constitutive and gemcitabine-induced NF-kappaB activity, enhanced caspase-3 activity, induced G(0)-G(1) phase arrest, and suppressed the expression of Bcl-2, Bcl-xL and surviving proteins. icariin caspase 3 Homo sapiens