Pub. Date : 2013 Jan 23
PMID : 23268743
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the TNF-alpha-induced 3T3-L1 adipocyte model, garcinol and pterostilbene significantly decreased the mRNA expression of COX-2, iNOS, IL-6, and IL-1beta and IL-6 secretion by suppressing phosphorylation of p-IkappaBalpha and p-p65. | pterostilbene | tumor necrosis factor | Homo sapiens |
| 2 | In a coculture model of 3T3-L1 adipocytes and RAW 264.7 macrophages, pterostilbene suppressed IL-6 and TNF-alpha secretion and proinflammatory mRNA expression and also reduced the migration of macrophages toward adipocytes. | pterostilbene | tumor necrosis factor | Homo sapiens |
| 3 | In the RAW 264.7 macrophage-derived conditioned medium (RAW-CM)-induced 3T3-L1 adipocyte and 3T3-CM-induced RAW 264.7 macrophage models, pterostilbene significantly decreased IL-6 and TNF-alpha secretion and proinflammatory mRNA expression (COX-2, iNOS, IL-6, TNF-alpha, PAI-1, CRP, MCP-1, resistin, and leptin). | pterostilbene | tumor necrosis factor | Homo sapiens |
| 4 | In the RAW 264.7 macrophage-derived conditioned medium (RAW-CM)-induced 3T3-L1 adipocyte and 3T3-CM-induced RAW 264.7 macrophage models, pterostilbene significantly decreased IL-6 and TNF-alpha secretion and proinflammatory mRNA expression (COX-2, iNOS, IL-6, TNF-alpha, PAI-1, CRP, MCP-1, resistin, and leptin). | pterostilbene | tumor necrosis factor | Homo sapiens |