Title : Loss of Par3 promotes breast cancer metastasis by compromising cell-cell cohesion.

Pub. Date : 2013 Feb

PMID : 23263278






1 Functional Relationships(s)
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1 However, loss of Par3 inhibited E-cadherin junction stability, disrupted membrane and actin dynamics at cell-cell junctions and decreased cell-cell cohesion in a manner dependent on the Tiam1/Rac-GTP pathway. Guanosine Triphosphate AKT serine/threonine kinase 1 Homo sapiens