Title : Lack of effect of propylthiouracil and methylmercaptoimidazole on thyroglobulin biosynthesis.

Pub. Date : 1990 May

PMID : 2326285






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1 Experiments were performed both in vivo and in vitro to test a previous proposal that part of the antithyroid action of the thioureylene drugs, propylthiouracil (PTU) and methylmercaptoimidazole, can be attributed to inhibition of thyroglobulin (Tg) biosynthesis. Propylthiouracil thyroglobulin Rattus norvegicus