Title : Effects of PPARĪ³ agonists on the expression of leptin and vascular endothelial growth factor in breast cancer cells.

Pub. Date : 2013 Jun

PMID : 23254958






2 Functional Relationships(s)
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1 Here, we studied if these compounds, ciglitazone and GW1929, can affect the expression of leptin and VEGF in breast cancer cells. ciglitazone leptin Homo sapiens
2 In MDA-MB-231 and MCF-7 breast cancer cells, treatment with submolar concentrations of ciglitazone and GW1929 elevated the expression of leptin and VEGF mRNA and protein, and increased cell viability and migration. ciglitazone leptin Homo sapiens