Title : Simvastatin abrogates inflamed neutrophil adhesive properties, in association with the inhibition of Mac-1 integrin expression and modulation of Rho kinase activity.

Pub. Date : 2013 Feb

PMID : 23250325






1 Functional Relationships(s)
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1 RESULTS: In the presence of a TNF-alpha inflammatory stimulus, neutrophils displayed a rapid and substantial enhancement in their adhesive properties that was abrogated by preincubation of cells with simvastatin. Simvastatin tumor necrosis factor Homo sapiens