Title : Tetrahydrobiopterin improves diastolic dysfunction by reversing changes in myofilament properties.

Pub. Date : 2013 Mar

PMID : 23247392






1 Functional Relationships(s)
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1 Evidence indicates that cardiac relaxation may depend on nitric oxide (NO), generated by NO synthase (NOS) requiring the co-factor tetrahydrobiopterin (BH(4)). sapropterin nitric oxide synthase 1, neuronal Mus musculus