Pub. Date : 2013 Jan
PMID : 23247124
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Pretreatment with IL-10 significantly decreased TNF-alpha-induced increased levels of ceramide (TNF-alpha vs. TNF-alpha + IL-10: 6,278 +- 1,013 vs. 1,440 +- 130 pmol/mg prot), as well as ICAM-1 expression and leukocyte adhesion (TNF-alpha vs. TNF-alpha + IL-10: 26.8 +- 2.6 vs. 6.7 +- 0.4 adherent leukocytes/field at 15 min). | Ceramides | tumor necrosis factor | Homo sapiens |
| 2 | Pretreatment with IL-10 significantly decreased TNF-alpha-induced increased levels of ceramide (TNF-alpha vs. TNF-alpha + IL-10: 6,278 +- 1,013 vs. 1,440 +- 130 pmol/mg prot), as well as ICAM-1 expression and leukocyte adhesion (TNF-alpha vs. TNF-alpha + IL-10: 26.8 +- 2.6 vs. 6.7 +- 0.4 adherent leukocytes/field at 15 min). | Ceramides | tumor necrosis factor | Homo sapiens |
| 3 | Pretreatment with IL-10 significantly decreased TNF-alpha-induced increased levels of ceramide (TNF-alpha vs. TNF-alpha + IL-10: 6,278 +- 1,013 vs. 1,440 +- 130 pmol/mg prot), as well as ICAM-1 expression and leukocyte adhesion (TNF-alpha vs. TNF-alpha + IL-10: 26.8 +- 2.6 vs. 6.7 +- 0.4 adherent leukocytes/field at 15 min). | Ceramides | tumor necrosis factor | Homo sapiens |
| 4 | Pretreatment with IL-10 significantly decreased TNF-alpha-induced increased levels of ceramide (TNF-alpha vs. TNF-alpha + IL-10: 6,278 +- 1,013 vs. 1,440 +- 130 pmol/mg prot), as well as ICAM-1 expression and leukocyte adhesion (TNF-alpha vs. TNF-alpha + IL-10: 26.8 +- 2.6 vs. 6.7 +- 0.4 adherent leukocytes/field at 15 min). | Ceramides | tumor necrosis factor | Homo sapiens |
| 5 | Pretreatment with IL-10 significantly decreased TNF-alpha-induced increased levels of ceramide (TNF-alpha vs. TNF-alpha + IL-10: 6,278 +- 1,013 vs. 1,440 +- 130 pmol/mg prot), as well as ICAM-1 expression and leukocyte adhesion (TNF-alpha vs. TNF-alpha + IL-10: 26.8 +- 2.6 vs. 6.7 +- 0.4 adherent leukocytes/field at 15 min). | Ceramides | tumor necrosis factor | Homo sapiens |
| 6 | The antioxidant effect of IL-10 is mediated through PI3-kinase and is paralleled by a decrease in ceramide synthesis induced by TNF-alpha. | Ceramides | tumor necrosis factor | Homo sapiens |