Title : Disruption of brain redox homeostasis in glutaryl-CoA dehydrogenase deficient mice treated with high dietary lysine supplementation.

Pub. Date : 2013 Jan

PMID : 23218171






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1 The results indicate that a disruption of redox homeostasis in the cerebral cortex and striatum of young Gcdh(-/-) mice exposed to increased Lys diet may possibly represent an important pathomechanism of brain injury in GA I patients under metabolic stress. Lysine glutaryl-Coenzyme A dehydrogenase Mus musculus