Title : De novo production of the flavonoid naringenin in engineered Saccharomyces cerevisiae.

Pub. Date : 2012 Dec 8

PMID : 23216753






1 Functional Relationships(s)
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1 Synthesis of aromatic amino acids was deregulated by alleviating feedback inhibition of 3-deoxy-d-arabinose-heptulosonate-7-phosphate synthase (Aro3, Aro4) and byproduct formation was reduced by eliminating phenylpyruvate decarboxylase (Aro10, Pdc5, Pdc6). Amino Acids, Aromatic 3-deoxy-7-phosphoheptulonate synthase ARO3 Saccharomyces cerevisiae S288C