Title : ROCK2 regulates bFGF-induced proliferation of SH-SY5Y cells through GSK-3β and β-catenin pathway.

Pub. Date : 2013 Jan 25

PMID : 23211630






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Y27632, a specific inhibitor of ROCK, decreased bFGF-induced proliferation. Y 27632 fibroblast growth factor 2 Homo sapiens
2 Furthermore, bFGF inactivated GSK-3beta through increasing the phosphorylation of Ser(9) on GSK-3beta, which is reversed by Y27632 through increased phosphorylation of Tyr(216) on GSK-3beta. Y 27632 fibroblast growth factor 2 Homo sapiens