Title : Lessons from the dissection of the activation functions (AF-1 and AF-2) of the estrogen receptor alpha in vivo.

Pub. Date : 2013 Jun

PMID : 23200732






1 Functional Relationships(s)
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1 These actions are mediated by the activation of estrogen receptors (ER) alpha (ERalpha) and beta (ERbeta), which regulate target gene transcription (genomic action) through two independent activation functions (AF)-1 and AF-2, but can also elicit rapid membrane initiated steroid signals (MISS). Steroids estrogen receptor 1 Homo sapiens