Title : Sodium hydrogen sulfide inhibits nicotine and lipopolysaccharide-induced osteoclastic differentiation and reversed osteoblastic differentiation in human periodontal ligament cells.

Pub. Date : 2013 May

PMID : 23192567






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 NaHS blocked nicotine and LPS-induced activation of p38, ERK, MKP-1, PI3K, PKC, and PKC isoenzymes, and NF-kappaB. Nicotine dual specificity phosphatase 1 Homo sapiens
2 The effects of H(2)S on nicotine- and LPS-induced osteoblastic and osteoclastic differentiation were remarkably reversed by MKP-1 enzyme inhibitor (vanadate) and expression inhibitor (triptolide). Nicotine dual specificity phosphatase 1 Homo sapiens