Pub. Date : 2013 Jan 18
PMID : 23188823
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Direct regulation of nephrin tyrosine phosphorylation by Nck adaptor proteins. | Tyrosine | NPHS1 adhesion molecule, nephrin | Homo sapiens |
| 2 | We have recently reported that tyrosine phosphorylation of the cytoplasmic tail of nephrin facilitates recruitment of Nck SH2/SH3 adaptor proteins and subsequent actin remodeling and that phosphorylation of the Nck binding sites on nephrin is decreased during podocyte injury. | Tyrosine | NPHS1 adhesion molecule, nephrin | Homo sapiens |
| 3 | We have recently reported that tyrosine phosphorylation of the cytoplasmic tail of nephrin facilitates recruitment of Nck SH2/SH3 adaptor proteins and subsequent actin remodeling and that phosphorylation of the Nck binding sites on nephrin is decreased during podocyte injury. | Tyrosine | NPHS1 adhesion molecule, nephrin | Homo sapiens |
| 4 | Furthermore, induced loss of Nck expression in podocytes in vivo is associated with a rapid reduction in nephrin tyrosine phosphorylation. | Tyrosine | NPHS1 adhesion molecule, nephrin | Homo sapiens |