Title : Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell death.

Pub. Date : 2012 Dec 11

PMID : 23185017






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The p53-inducible protein TIGAR (Tp53-induced Glycolysis and Apoptosis Regulator) functions as a fructose-2,6-bisphosphatase (Fru-2,6-BPase), and through promotion of the pentose phosphate pathway, increases NADPH production to help limit reactive oxygen species (ROS). Pentosephosphates tumor protein p53 Homo sapiens