Title : Atorvastatin modulates the DDAH1/ADMA system in high-fat diet-induced insulin-resistant rats with endothelial dysfunction.

Pub. Date : 2012 Dec

PMID : 23184902






3 Functional Relationships(s)
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1 Atorvastatin modulates the DDAH1/ADMA system in high-fat diet-induced insulin-resistant rats with endothelial dysfunction. Atorvastatin dimethylarginine dimethylaminohydrolase 1 Rattus norvegicus
2 We aimed to determine the effects of atorvastatin, an endothelium-protective drug, on DDAH1/ADMA in insulin-resistant rats. Atorvastatin dimethylarginine dimethylaminohydrolase 1 Rattus norvegicus
3 In conclusion, our results suggest that atorvastatin may modulate DDAH1/ADMA to improve endothelial function in insulin-resistant rats; SREBP1 may also play a role in this. Atorvastatin dimethylarginine dimethylaminohydrolase 1 Rattus norvegicus