Pub. Date : 2013
PMID : 23179835
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In response to an inflammatory stimulus like LPS, M1 macrophages produce inducible nitric oxide synthase (iNOS) which uses L-arginine as a substrate to produce nitric oxide (NO). | Arginine | nitric oxide synthase 2, inducible | Mus musculus |
| 2 | In response to an inflammatory stimulus like LPS, M1 macrophages produce inducible nitric oxide synthase (iNOS) which uses L-arginine as a substrate to produce nitric oxide (NO). | Arginine | nitric oxide synthase 2, inducible | Mus musculus |
| 3 | M2 macrophages constitutively produce the enzyme arginase I (argI), which sequesters L-arginine from iNOS and results in the production of ornithine and downstream polyamines and L-proline. | Arginine | nitric oxide synthase 2, inducible | Mus musculus |