Pub. Date : 2013 Jun
PMID : 23177026
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | miR-21 expression in cancer tissue has been reported to be associated with the clinical outcome and activity of gemcitabine in pancreatic cancer. | gemcitabine | microRNA 21 | Homo sapiens |
2 | We tested the levels of serum miR-21 in a cohort of 177 cases of advanced pancreatic cancer who received gemcitabine-based palliative chemotherapy. | gemcitabine | microRNA 21 | Homo sapiens |
3 | The results from a functional study showed that gemcitabine exposure down-regulated miR-21 expression and up-regulated FasL expression. | gemcitabine | microRNA 21 | Homo sapiens |
4 | The increased FasL expression following gemcitabine treatment induced cancer cell apoptosis, whereas the ectopic expression of miR-21 partially protected the cancer cells from gemcitabine-induced apoptosis. | gemcitabine | microRNA 21 | Homo sapiens |