Title : Salinomycin induces cell death and differentiation in head and neck squamous cell carcinoma stem cells despite activation of epithelial-mesenchymal transition and Akt.

Pub. Date : 2012 Nov 24

PMID : 23176396






1 Functional Relationships(s)
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1 Contrary to expectations, salinomycin induced the expression of EMT markers Snail, vimentin, and Zeb-1, decreased expression of E-cadherin, and also induced phosphorylation of Akt and its downstream targets GSK3-beta and mTOR. salinomycin snail family transcriptional repressor 1 Homo sapiens