Title : Upregulation of ERCC1 and DPD expressions after oxaliplatin-based first-line chemotherapy for metastatic colorectal cancer.

Pub. Date : 2012 Dec 4

PMID : 23169295






1 Functional Relationships(s)
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1 In validation study, ERCC1 and DPD but not TOP1 expressions in cancer cells were significantly higher in FOLFOX (oxaliplatin, folinic acid, and 5-FU)-treated patients (N=24) than nontreated patients (N=21). Fluorouracil ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens