Pub. Date : 1990 Mar
PMID : 2316667
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Release of beta-glucuronidase, a lysosomal enzyme released by osteoclasts, increased after a 24-h incubation in aluminum-containing medium and was correlated with net calcium efflux. | Aluminum | glucuronidase, beta | Mus musculus |
2 | Thus aluminum induces cell-mediated net calcium efflux from bone and increases beta-glucuronidase release. | Aluminum | glucuronidase, beta | Mus musculus |
3 | Calcitonin inhibits the increase in both calcium efflux and beta-glucuronidase release, suggesting that aluminum stimulates osteoclasts to release bone mineral. | Aluminum | glucuronidase, beta | Mus musculus |